SOS1-IN-14 is a potent, selective and orally active SOS1 inhibitor with an IC50 value of 3.9 nM. SOS1-IN-14 can be absorbed in the intestine via a P-glycoprotein-mediated efflux mechanism. SOS1-IN-14 can be used to research KRAS-mutated cancers. SOS1-IN-14 has better potent tumor suppression than BI-3406 (HY-125817)[1].
Molecular Weight:
550.57
Purity:
99.60
CAS Number:
[2793405-20-4]
Formula:
C29H29F3N6O2
Target:
Ras,SOS1
Application Notes:
MCE Product type: Reference compound
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