MRS4719-d3 is the deuterium labeled MRS4719 (HY-151547). MRS4719 is a potent P2X4 receptor antagonist with an IC50 value of 0.503 µM for human P2X4 receptor. MRS4719 can reduce infarct volume and reduce brain atrophy, showing neuroprotective and neuro-rehabilitative activities in ischemic stroke model. MRS4719 also reduces ATP-induced [Ca2+]i influx in primary human monocyte-derived macrophages. MRS4719 can be used to research ischemic stroke[1].
Molecular Weight:
507.62
Formula:
C26H25D3N6O3S
Target:
Isotope-Labeled Compounds,P2X Receptor
Application Notes:
MCE Product type: Isotope-Labeled Compounds
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