Akt3 degrader 1 (compound 12l) is a selective Akt3 degrader that overcomesOsimertinib (HY-15772)-induced resistance in H1975OR NSCLC cells. Akt3 degrader 1 also has anti-proliferative activity and significantly inhibits tumour growth in mice. Akt3 degrader 1 can be used in the study of drug-resistant non-small cell lung cancer[1].
Molecular Weight:
885.19
Purity:
99.43
CAS Number:
[2836342-69-7]
Formula:
C53H72N8O4
Target:
Akt
Application Notes:
MCE Product type: Reference compound1
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