Monomethyl auristatin E (MMAE, SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.
Molecular Weight:
717.98
Purity:
99.98
CAS Number:
[474645-27-7]
Formula:
C39H67N5O7
Target:
ADC Payload,Apoptosis,Microtubule/Tubulin
Application Notes:
MCE Product type: ADC Related
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