ACBI2 is a highly potent and orally active VHL PROTAC SMARCA2 degrader (EC50: 7 nM), which selectively degrades SMARCA2 with a DC50 value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer[1].
Molecular Weight:
1064.16
Purity:
99.76
CAS Number:
[2913161-19-8]
Formula:
C56H68BrFN8O5S
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
MCE Product type: Reference compound
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