Monomethyl auristatin E (MMAE) (Standard) is the analytical standard of Monomethyl auristatin E (HY-15162). This product is intended for research and analytical applications. Monomethyl auristatin E is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) against several different cancer types[1].
Molecular Weight:
717.98
Purity:
99.99
CAS Number:
[474645-27-7]
Formula:
C39H67N5O7
Target:
Apoptosis,Microtubule/Tubulin,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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