Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (Kd=490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells[1][2].
Molecular Weight:
778.94
Purity:
99.95
CAS Number:
[1781882-65-2]
Formula:
C31H37Cl5N8O5
Target:
G-quadruplex
Application Notes:
MCE Product type: Reference compound1
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