CPUL1 is a TrxR inhibitor, which shows proliferation-inhibitory and anti-metastatic activity against A549 cells. CPUL1 influences EMT (epithelial-mesenchymal transition) via inducing ROS-mediated ERK/JNK signaling by inhibiting TrxR1 enzyme activity. CPUL1 in combination with alpha-Lipoic Acid (HY-N0492) or Dithiodipropionic acid (HY-W014395) is more effective[1].
Molecular Weight:
434.28
CAS Number:
[2043660-80-4]
Formula:
C22H13Cl2N5O
Target:
TrxR
Application Notes:
MCE Product type: Reference compound
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