NNMT-IN-4 (compound 38) is a selective, uncompetitive and membrane permeability nicotinamide N-methyltransferase (NNMT) inhibitor with IC50 values of 42 and 38 nM in vitro biochemical and cell-based assays, respectively. NNMT-IN-4 shows favorable PK/PD and safety profiles as well as excellent oral bioavailability and pharmaceutical properties. NNMT-IN-4 can be used as a vivo chemical probe of NNMT[1].
Molecular Weight:
177.20
Purity:
99.35
CAS Number:
[2947393-64-6]
Formula:
C9H11N3O
Target:
Fluorescent Dye
Application Notes:
Reference compound
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