Nirogacestat (Standard) is the analytical standard of Nirogacestat. This product is intended for research and analytical applications. Nirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective gamma-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers[1].
Molecular Weight:
489.64
CAS Number:
[1290543-63-3]
Formula:
C27H41F2N5O
Target:
Apoptosis,Reference Standards,gamma-secretase
Application Notes:
MCE Product type: Reference Standards
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