NLRP3-IN-12 is a specific NLRP3 inflammasome inhibitor. NLRP3-IN-12 reduces the release of IL-1beta by targeting the NLRP3 protein, with an IC50 of 0.45 µM. NLRP3-IN-12 can be used for the research of inflammatory bowel disease[1].
Molecular Weight:
518.00
Formula:
C27H32ClNO7
Target:
NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound1
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