FXR agonist 4 (compound 10a) is an agonist of farnesoid X receptor (FXR) with an EC50 value of 1.05 µM. FXR agonist 4 effectively improves hyperlipidemia, hepatic steatosis, insulin resistance and hepatic inflammation in DIO mice. FXR agonist 4 can be used for the research of non-alcoholic fatty liver disease (NAFLD)[1].
Molecular Weight:
373.92
Purity:
99.37
CAS Number:
[3025841-47-5]
Formula:
C21H28ClN3O
Target:
FXR
Application Notes:
MCE Product type: Reference compound
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