MRK 003 is a potent, selective and orally active gamma-secretase inhibitor. MRK 003 reduce brain Abeta production in vivo. MRK 003 induces caspase-dependent apoptosis and inhibits tumor cell proliferation in vivo and in vitro[1][2][3].
Molecular Weight:
551.59
CAS Number:
[623165-93-5]
Formula:
C25H31F6N3O2S
Target:
Apoptosis,gamma-secretase
Application Notes:
MCE Product type: Reference compound
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