AChE/BChE/MAO-B-IN-4, an indan-1-one derivative, is a potent MAO-B inhibitor with an IC50 of 0.0393 µM for human MAO-B. AChE/BChE/MAO-B-IN-4 is a potent AChE and BChE enzyme inhibitor, with IC50s of 0.0458 µM and 0.075 µM for human AChE and BChE enzyme, respectively. AChE/BChE/MAO-B-IN-4 shows significant antioxidant activity and prevent beta-amyloid plaque aggregation. AChE/BChE/MAO-B-IN-4 has the potential for Alzheimers disease (AD) research[1].
Molecular Weight:
451.56
Formula:
C26H33N3O4
Target:
Cholinesterase (ChE),Monoamine Oxidase
Application Notes:
MCE Product type: Reference compound1
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