SZUH280 is a potent and selective PROTAC HDAC8 degrader with a DC50 of 0.58 µM in A549 cells. SZUH280 induces cancer cell apoptosis. SZUH280 hampers DNA damage repair in cancer cells, promoting cellular radiosensitization[1].
Molecular Weight:
706.70
Purity:
99.38
CAS Number:
[2770263-77-7]
Formula:
C36H34N8O8
Target:
Apoptosis,DNA/RNA Synthesis,HDAC,PROTACs
Application Notes:
MCE Product type: Reference compound
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