JZP-MA-11 is a positron emission tomography (PET) ligand targeting the endocannabinoid alpha/beta-hydrolase domain 6 (ABHD6) enzyme. JZP-MA-11 selectively inhibits ABHD6 with an IC50 value of 126 nM. JZP-MA-11 can cross the blood-brain barrier (BBB). [18F]JZP-MA-11 has the potential for preclinical evaluation targeting the brain ABHD6 in mice and nonhuman primate (NHP)[1].
Molecular Weight:
336.38
Purity:
99.26
CAS Number:
[1672691-50-7]
Formula:
C15H17FN4O2S
Target:
MAGL
Application Notes:
MCE Product type: Reference compound
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