LWG-301 is an allosteric inhibitor of Glutaminase 1 (GLS1) with an IC50 value of 7 nM. LWG-301 significantly block glutamine metabolism, increases intracellular ROS, thus induces apoptosis. LWG-301 exhibits moderate antitumor effects in HCT116 xenograft model[1].
Molecular Weight:
566.72
CAS Number:
[3038480-88-2]
Formula:
C28H38N8O3S
Target:
Apoptosis,Glutaminase
Application Notes:
MCE Product type: Reference compound
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