BPDA2 is a highly selective and competitive active site SHP2 inhibitor with IC50s of 92.0 nM, 33.39 µM, 40.71 µM for SHP2, SHP1, SHP1B, respectively. DBDA2 downregulates mitogenic and cell survival signaling and RTK expression. BPDA2 suppresses SHP2 mediated signaling and breast cancer cell phenotypes[1].
Molecular Weight:
398.49
Purity:
99.30
CAS Number:
[2907659-86-1]
Formula:
C24H30O5
Target:
SHP1,SHP2
Application Notes:
MCE Product type: Reference compound
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