Methylstat is a potent histone demethylases inhibitor. Methylstat shows anti-proliferative activity with low cytotoxicity. Methylstat induces apoptosis and cell cycle arrest at G0/G1 phase. Methylstat increases the expression of p53 and p21 protein levels. Methylstat inhibits angiogenesis induced by various cytokines. Methylstat can be used as a chemical probe for addressing its role in angiogenesis[1][2].
Molecular Weight:
505.56
Purity:
99.85
CAS Number:
[1310877-95-2]
Formula:
C28H31N3O6
Target:
Apoptosis,Histone Demethylase,MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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