BET-IN-13 is a potent BET inhibitor with an IC50 value of 1.6 nM. BET-IN-13 reduces LPS-induced TNF-alpha, IL-1beta, IL-6, and NOS2 mRNA expression levels. BET-IN-13 shows anti-inflammatory activity. BET-IN-13 has the potential for the research of acute liver injury[1].
Molecular Weight:
497.56
CAS Number:
[2506823-08-9]
Formula:
C28H23N3O4S
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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