PCSK9-IN-11 (compound 5r) is a potent and orally active PCSK9 inhibitor. PCSK9-IN-11 exhibits PCSK9 transcriptional inhibitory activity in HepG2 cells, with an IC50 of 5.7 µM. PCSK9-IN-11 increases LDL receptor (LDLR) protein level. PCSK9-IN-11 can be used for atherosclerosis research[1].
Molecular Weight:
381.79
Purity:
99.30
CAS Number:
[2882035-56-3]
Formula:
C16H17ClFN5O3
Target:
PCSK9
Application Notes:
MCE Product type: Reference compound
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