Menin-MLL inhibitor MI-2 (dihydrochloride) Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-15222A
Supplier Catalog Number:
HY-15222A
Alternative Catalog Number:
MCE-HY-15222A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Menin-MLL inhibitor MI-2 dihydrochloride is a competitive and selective Menin-MLL interaction inhibitor with an IC50 value of 446 nM and a Ki value of 158 nM. Menin-MLL inhibitor MI-2 dihydrochloride downregulates the expression of target genes such as HOXA9 and MEIS1, inhibits proliferation of leukemia cells and induces apoptosis and differentiation. Menin-MLL inhibitor MI-2 dihydrochloride is proming for rasearch of MLL-rearranged acute leukemias (e.g., AML, ALL)[1].
Molecular Weight:
448.48
Formula:
C18H27Cl2N5S2
Target:
Apoptosis,Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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