PD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions, induces PD-L1 dimerization and internalization, improves its localization to the endoplasmic reticulum, and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity[1].
Molecular Weight:
460.48
Purity:
99.87
CAS Number:
[2665734-13-2]
Formula:
C26H24N2O6
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound1
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