Zidesamtinib (NVL-520) is a potent, selective, orally active and brain-penetrant inhibitor of diverse ROS1 fusions and resistance mutations, with IC50s of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and spares TRK inhibition. Zidesamtinib can be used for the research of cancer[1].
Molecular Weight:
419.45
Purity:
99.55
CAS Number:
[2739829-00-4]
Formula:
C22H22FN7O
Target:
ROS Kinase
Application Notes:
MCE Product type: Reference compound
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