6-O-Methylinosine is a hypoxanthine analogue. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].
Molecular Weight:
282.25
CAS Number:
[5746-29-2]
Formula:
C11H14N4O5
Target:
Nucleoside Antimetabolite/Analog,Xanthine Oxidase
Application Notes:
MCE Product type: Oligonucleotides
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