WYE-687 dihydrochloride is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM[1]. WYE-687 dihydrochloride concurrently inhibits activation of mTORC1 and mTORC2[2]. WYE-687 also inhibits PI3Kalpha and PI3Kgamma with IC50s of 81 nM and 3.11 µM, respectively[1].
Molecular Weight:
601.53
Purity:
98
CAS Number:
[1702364-87-1]
Formula:
C28H34Cl2N8O3
Target:
mTOR,PI3K
Application Notes:
MCE Product type: Reference compound
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