Izumerogant (IMU-935) is an orally active RORgamma/DHODH dual inhibitor with IC50s of 10 and 98 nM against RORgamma and DHODH. Izumerogant efficiently blocks the replication of SARS-CoV-2, HCMV and HAdV5 with EC50 values between 3.6 and 17 nM. Izumerogant can be used for researching antiviral properties[1][2].
Molecular Weight:
495.86
Purity:
99.95
CAS Number:
[2299252-72-3]
Formula:
C22H18ClF4N5O2
Target:
CMV,Dihydroorotate Dehydrogenase,ROR,SARS-CoV
Application Notes:
MCE Product type: Reference compound1
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