MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinsons disease[1].
Molecular Weight:
332.32
Purity:
99.45
CAS Number:
[2499962-58-0]
Formula:
C17H15F3N4
Target:
Mitochondrial Metabolism,Mitophagy,PINK1/Parkin
Application Notes:
MCE Product type: Reference compound
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