TMX-4153 is a selective PIP4K2C PROTAC degrader. TMX-4153 induces PIP4K2C degradation in MOLT4 cells (DC50 = 24 nM) and HAP1 cells (DC50 = 361 nM). TMX-4153 can be used for the study of biological functions of PIP4K2C (immune modulation)-related diseases. (Pink: BTK ligand (HY-177432), Blue: VHL Ligand (HY-112078), Black: Linker)[1].
Molecular Weight:
1079.74
Purity:
98.96
CAS Number:
[2867519-91-1]
Formula:
C59H67ClN10O6S
Target:
PIKfyve,PROTACs
Application Notes:
MCE Product type: Reference compound
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