Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas[1][2].
Molecular Weight:
420.19
Purity:
98
CAS Number:
[147254-64-6]
Formula:
C17H11BrFN3O4
Target:
Aldose Reductase
Application Notes:
MCE Product type: Reference compound
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