PT-65 is a GSK3alpha and GSK3beta PROTAC degrader with DC50 values of 28.3 nM and 34.2 nM, respectively. PT-65 inhibits excessive tau phosphorylation mediated by GSK3beta, Abeta and Okadaic acid (HY-N6785). PT-65 is applicable for the research of Alzheimers disease[1].
Molecular Weight:
1082.19
Purity:
99.48
CAS Number:
[2721998-87-2]
Formula:
C51H63N13O12S
Target:
GSK-3,PROTACs,Tau Protein
Application Notes:
MCE Product type: Reference compound
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