PT-65 is a potent and selective GSK3 PROTAC degrader with the highest degradation capacity of GSK3alpha (DC50= 28.3 nM) and GSK3beta (DC50= 34.2 nM) in SH-SY5Y cells. PT-65 can be used in Alzheimers disease research[1].(Pink: GSK3 inhibitor (HY-15761), Black: linker, Blue: CRBN Ligand (HY-10984))
Molecular Weight:
1082.19
Purity:
99.48
CAS Number:
[2721998-87-2]
Formula:
C51H63N13O12S
Target:
GSK-3,PROTACs
Application Notes:
MCE Product type: Reference compound1
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