JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 µM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity[1].
Molecular Weight:
292.12
Purity:
99.75
CAS Number:
[339103-05-8]
Formula:
C13H7Cl2N3O
Target:
FOXO
Application Notes:
Reference compound
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