Timapiprant (OC000459) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant (OC000459) potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant (OC000459) inhibits mast cell activation of Th2 lymphocytes and eosinophils[1].
Molecular Weight:
348.37
Purity:
98.12
CAS Number:
[851723-84-7]
Formula:
C21H17FN2O2
Target:
Prostaglandin Receptor
Application Notes:
MCE Product type: Reference compound
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