IBG1 is a molecular glue degrader targeting BRD2 and BRD4 (DC50: 0.15 nM). IBG1 has no significant degradation effect on its paralogue BRD3. IBG1 can inhibit the growth of cancer cells and can be used in tumor research. (Pink: BRD2/BRD4 Ligand (HY-111139), Black: Linker, Blue: DCAF15 ligand-1 (HY-W037495))[1][2].
Molecular Weight:
822.95
Purity:
98.83
CAS Number:
[2684292-71-3]
Formula:
C44H38N8O5S2
Target:
Epigenetic Reader Domain,Molecular Glues
Application Notes:
Reference compound
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