TLR7/8/9 antagonist 2 is an orally active TLR7/8/9 antagonist. TLR7/8/9 antagonist 2 has inhibitory activities for HEK/hTLR7, HEK/hTLR8 and HEK/hTLR9 with IC50 values of 0.011 µM, 0.029 µM and 0,052 µM, respectively.TLR7/8/9 antagonist 2 has high bioavailability in vivo.TLR7/8/9 antagonist 2 can be used for the research of auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis[1].
Molecular Weight:
405.54
Purity:
98.96
CAS Number:
[2920729-91-3]
Formula:
C23H31N7
Target:
Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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