Hi 76-0079 (NNC0076-0079, 76-0079) is a lipase inhibitor that specifically targets hormone-sensitive lipase (HSL). Hi 76-0079 inhibits PNPB Hydrolysis in cell lysates of HEK293A cells overexpressing Lipe with an IC50 value of 0.1 µM. Hi 76-0079 synergizes with the ATGL inhibitor Atglistatin (HY-15859) to block lipolysis in vitro. Hi 76-0079 can be used for the study of lipid metabolism[1][2].
Molecular Weight:
256.69
Purity:
99.90
CAS Number:
[374567-94-9]
Formula:
C11H13ClN2O3
Target:
Lipase
Application Notes:
Reference compound
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