TLR7/8 agonist 8 (compound 24m) is a potent toll-like receptor 7/8 (TLR7/8) dual agonist, with EC50s of 27 and 12 nM for hTLR7 and hTLR8, respectively. TLR7/8 agonist 8 can improve the antitumor activity of PD-1/PD-L1 blockade[1].
Molecular Weight:
418.53
Purity:
98.69
CAS Number:
[2649170-16-9]
Formula:
C24H30N6O
Target:
Toll-like Receptor (TLR)
Application Notes:
Reference compound
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