TH-Z827 is a mutant selective KRAS(G12D) inhibitor with an IC50 of 2.4 µM. TH-Z827 does not bind KRAS(WT) or KRAS(G12C). TH-Z827 blocked the KRAS(G12D)-CRAF interaction with an IC50 value of 42 µM[1].
Molecular Weight:
498.66
Purity:
95.12
CAS Number:
[2847881-81-4]
Formula:
C30H38N6O
Target:
Ras
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted