CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. CC-3060 degrades ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 targets ZBTB16 for degradation by primarily engaging distinct structural degrons on different zinc finger domains[1].
Molecular Weight:
403.39
Purity:
99.7
CAS Number:
[444288-86-2]
Formula:
C22H17N3O5
Target:
Ligands for E3 Ligase
Application Notes:
MCE Product type: Reference compound
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