Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 µM for type I adenylyl cyclase[1]. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy[4][5].
Molecular Weight:
410.50
Purity:
99.94
CAS Number:
[66575-29-9]
Formula:
C22H34O7
Target:
Adenylate Cyclase,Autophagy,FXR,Organoid,PKC
Application Notes:
MCE Product type: Natural Products
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