Navepdekinra (DC-806) is an orally active, potent interleukin-17A (IL-17A) inhibitor (IC50 = 10.81 nM). Navepdekinra disrupts the IL-17A protein-receptor interaction, suppressing the downstream pro-inflammatory signaling pathway. Navepdekinra inhibits arthritis in a collage-induced arthritis (CIA) rat model. Navepdekinra can be used for psoriasis, psoriatic arthritis, and ankylosing spondylitis[1][2][3].
Molecular Weight:
625.78
Purity:
98.58
CAS Number:
[2467732-66-5]
Formula:
C33H48FN7O4
Target:
Interleukin Related
Application Notes:
MCE Product type: Reference compound
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