rTRD01 is a TDP-43 ligand that binds to TDP-43s RRM1 and RRM2 domains (Kd=89 uM for TDP-43102-269). rTRD01 partially disrupts TDP-43s interaction with the hexanucleotide RNA repeat of the disease-linked c9orf72 gene. rTRD01 can be used for the research of neurodegenerative diseases[1].
Molecular Weight:
344.38
Purity:
99.10
CAS Number:
[1332175-56-0]
Formula:
C18H21FN4O2
Target:
Amyloid-beta
Application Notes:
MCE Product type: Reference compound
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