(R)-SKBG-1, CAS [[2955634-67-8]]

Product Overview

• Article Name: (R)-SKBG-1, CAS [[2955634-67-8]]
• Biozol Catalog Number: MCE-HY-153918
• Supplier Catalog Number: HY-153918
• Alternative Catalog Number: MCE-HY-153918-100MG,MCE-HY-153918-25MG,MCE-HY-153918-10MG,MCE-HY-153918-5MG,MCE-HY-153918-50MG,MCE-HY-153918-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

(R)-SKBG-1 is a covalent inhibitor targeting the RNA binding protein NONO. (R)-SKBG-1 can reduce the expression of androgen receptor (AR) and its splice variants, inhibiting cancer cell proliferation. (R)-SKBG-1 inhibits androgen receptor expression with IC50 of 3.1 µM and 5.5 µM for AR-FL mRNA and AR-V7 mRNA, respectively. (R)-SKBG-1 interferes with the gene regulatory network of cancer cells and inhibits cancer cell growth by stabilizing the interaction between NONO and mRNA. (R)-SKBG-1 can be used in the study of cancers related to NONO dysfunction, such as prostate cancer[1][2][3].

Product Properties

• Molecular Weight: 495.98
• Purity: 99.50
• CAS Number: [2955634-67-8]
• Formula: C22H26ClN3O6S
• Target: Androgen Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound