Tezacaftor-d6, CAS [[1961280-94-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-15448S1
Supplier Catalog Number:
HY-15448S1
Alternative Catalog Number:
MCE-HY-15448S1-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
VX-661-d6
Tezacaftor-d6 (VX-661-d6) is deuterium labeled Tezacaftor. Tezacaftor (VX-661) is a F508del CFTR corrector. It helps CFTR protein reach the cell surface. However, Ivacaftor (VX-770, HY-13017), a CFTR potentiator, helps to prolong the opening time of cell surface CFTR protein channels. Tezacaftor combining with Ivacaftor, shows potent efficacy against cystic fibrosis and diseases with homozygous for the CFTR Phe508del mutation. Moreover, Elexacaftor (VX-445, HY-111772) is also a CFTR corrector. Elexacaftor-Tezacaftor-Ivacaftor aims at with cystic fibrosis (CF) with at least one Phe508del mutation, often avoids the indication for lung transplantation[1][2][3][4].
Molecular Weight:
526.53
CAS Number:
[1961280-94-3]
Formula:
C26H21D6F3N2O6
Target:
CFTR,Isotope-Labeled Compounds
Application Notes:
Isotope-Labeled Compounds
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