Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDE4A4, PDE4B1, and PDE4B2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.
Molecular Weight:
403.21
Purity:
99.98
CAS Number:
[162401-32-3]
Formula:
C17H14Cl2F2N2O3
Target:
Phosphodiesterase (PDE),RSV
Application Notes:
MCE Product type: Reference compound
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