YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac beta-adrenoceptors[1][2][3].
Molecular Weight:
386.28
Purity:
99.98
CAS Number:
[132836-42-1]
Formula:
C20H20BrNO2
Target:
Adrenergic Receptor,Akt,Angiotensin Receptor,PI3K
Application Notes:
MCE Product type: Reference compound
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