DQn-1 is a potent antifolate with activity against Mycobacterium tuberculosis (Mtb) (MIC90=0.03 µM). DQn-1 directly inhibits DHFR enzyme activity, with IC50s of 8.7 and 7.6 nM for Mtb and human DHFR enzyme, respectively[1].
Molecular Weight:
343.77
CAS Number:
[57343-54-1]
Formula:
C16H14ClN5O2
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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