JET-209, CAS [[3033714-58-5]]

Product Overview

• Article Name: JET-209, CAS [[3033714-58-5]]
• Biozol Catalog Number: MCE-HY-154984
• Supplier Catalog Number: HY-154984
• Alternative Catalog Number: MCE-HY-154984-10MG,MCE-HY-154984-1MG,MCE-HY-154984-5MG,MCE-HY-154984-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

JET-209 is a potent CBP/p300 PROTAC degrader, with DC50 values of 0.05 nM and 0.2 nM for CBP and p300. JET-209 demonstrates remarkable anti-tumor activity against various acute leukemia cell lines and effectively inhibits tumor growth in xenograft tumor models. JET-209 can be used for the study of acute leukemia (Pink: CBP/p300 ligand (HY-175620), Blue: CRBN ligand (HY-132248), Black: Linker, CBP/p300 ligand + Linker (HY-175621))[1].

Product Properties

• Molecular Weight: 821.92
• Purity: 98.09
• CAS Number: [3033714-58-5]
• Formula: C46H47N9O6
• Target: Histone Acetyltransferase,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound