EGFR mutant-IN-2 (Compound D51) is an EGFR mutant inhibitor. EGFR mutant-IN-2 inhibits the EGFRL858R/T790M/C797S mutant with an IC50 value of 14 nM. EGFR mutant-IN-2 inhibits the EGFRdel19/T790M/C797S mutant with an IC50 value of 62 nM. EGFR mutant-IN-2 has favorable PK parameters, safety properties, in vivo stability, and antitumor activity[1].
Molecular Weight:
556.60
Purity:
97
CAS Number:
[2770009-06-6]
Formula:
C27H27F3N6O2S
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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