Mcl-1 inhibitor 16 (Compound 9) is a mitochondrial targeting Platinum-based inhibitor of Mcl-1. Mcl-1 inhibitor 1 induces Bax/Bak-dependent apoptosis in cancer cells. Mcl-1 inhibitor 16 can be used alone or together with ABT-199 (HY-15531) and shows anti-tumor activity[1].
Molecular Weight:
637.51
Formula:
C25H29Cl2N3Pt
Target:
Bcl-2 Family
Application Notes:
MCE Product type: Reference compound
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